Lorenzo Madeddu
Lorenzo Madeddu
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2
Deep Graph Networks for Drug Repurposing with Multi-Protein Targets
Developed a novel deep graph learning method for drug-target interaction prediction. Demonstrated an application of our method to repurpose existing drugs against the COVID-19 virus.
Davide Bacciu
,
Federico Errica
,
Alessio Gravina
,
Lorenzo Madeddu
,
Marco Podda
,
Giovanni Stilo
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A Network-Based Analysis of Disease Modules from a Taxonomic Perspective
Developed a methodology and related algorithms to automatically induce a hierarchical structure of disease modules from proximity relations in the interactome network, and to align, label, and systematically compare this structure with a manually defined disease ontology.
Giorgio Grani
,
Lorenzo Madeddu
,
Paola Velardi
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A Feature-Learning-Based Method for the Disease-Gene Prediction Problem
Developed a deep graph learning-based model for predicting disease-gene associations. The model jointly learns functional and connectivity patterns using a novel technique based on attributed random walks.
Lorenzo Madeddu
,
Giovanni Stilo
,
Paola Velardi
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